Santhakumaran Thampi Foundation was formed in 2006 with Bangalore as its center. The foundation started its activities by organizing literary conferences and book discussions in the city of Bangalore. Since 2008 annual literary conferences are being held. 

 In 2012, under the auspices of the foundation, Santham masika( SANTHAM MAGAZINE) started publication in print.  

One of the foundation’s proudest achievements is introducing and implementing the concept of Mega Literature Festival for the first time in Kerala. 

The third and fourth Editions of Palakkad Literature Festival(known as PLF) organized in 2017 and 2018 at Fort maidan, Palakkad, gained widespread attention.  

Santham Cultural Forum, an organization of readers, writers and cultural/social workers organizes several cultural events.  

Santham award is distributed every year to senior artists working in the fields of art, literature and culture.  

 The foundation also conducts philanthropic activities, counseling for students, lecture series, literary writing workshops, painting camps, folk art programmes, field trips etc.